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de-la-Cruz, Miriel; Millan-Aldaco, Diana; Marcia Soriano-Nava, Daniela; Drucker-Colin, Rene; Murillo-Rodriguez, Eric (2018)

THE ARTIFICIAL SWEETENER SPLENDA INTAKE PROMOTES CHANGES IN EXPRESSION OF C-FOS AND NEUN IN HYPOTHALAMUS AND HIPPOCAMPUS OF RATS

Brain Res. 1700():181-189
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Obesity is the result of the interaction of multiple variables, including the excessive increase of sugar-sweetened beverages consumption. Diets aimed to treat obesity have suggested the use of artificial sweeteners. However, recent evidence has shown several health deficits after intake of artificial sweeteners, including effects in neuronal activity. Therefore, the influence of artificial sweeteners consumption such as Splenda, on the expression of c-Fos and neuronal nuclear protein (NeuN) in hypothalamus and hippocampus remains to be determined.