Tibolone Administration Is Associated with Enhanced Motor Recovery and Decreased Cell-Specific NOX2 and NOX4 Immunoreactivity in a Rat Model of Traumatic Spinal Cord Injury.
Castillo-Mendieta, T., Sánchez-Torres, S., Salgado-Ceballos, H., Segura-Uribe, J. J., Morán, J., Guerra-Araiza, C., & Coyoy-Salgado, A. (2026). Tibolone Administration Is Associated with Enhanced Motor Recovery and Decreased Cell-Specific NOX2 and NOX4 Immunoreactivity in a Rat Model of Traumatic Spinal Cord Injury. Brain Sciences, 16(7), 711. https://doi.org/10.3390/brainsci16070711
ABSTRACT
This study aimed to investigate the effect of tibolone (TIB) on the expression of the NOX2 and NOX4 isoforms and their co-localization in neurons and astrocytes using an animal model of spinal cord injury (SCI).